The boys plan to get rich off a scheme involving the Tooth Fairy, which attracts the attention of an unusual crime boss. Meanwhile, Kyle ponders his existence after his parents tell him the truth about the Tooth fairy.
Cartman gets arrested for a hate crime and is sent to a Juvenile Detention prison.
All the kids in South Park are mistakenly diagnosed with attention deficit disorder after the new, mentally retarded student Timmy is misdiagnosed himself. Meanwhile, Timmy joins Skyler's rock band, and Phil Collins plots to break them up.
Stan's family take in a grandmother and her quintuplet granddaughters from Romania who are on the run from the American and Romanian government. Meanwhile, Kenny practices opera singing.
Cartman's search for more mature friends lands him as the poster child for NAMBLA. Meanwhile, Kenny tries to stop his parents from having another baby.
Stan must get Cartman to donate one of his kidneys to save Kyle's life while everyone in town is addicted to new-age medicine run by an old woman and her "Native American" co-workers. Meanwhile, Mr. Garrison becomes a romance novelist after getting fired from teaching for his incompetence and his actions in the previous episode.
Chef protests against the racist imagery on the South Park flag. Meanwhile, Wendy freaks out when she begins to have a crush on Cartman.
Cartman ropes in Stan, Kyle, and Kenny into creating Finger Bang, a boy band in the quest to get $10 million.
The boys question whether the handicapped or Jews go to heaven, while Saddam Hussein returns to hell, leading to an awkward reunion with Satan.
Cartman and the boys start their own church against the wishes of their parents; Satan must choose between two lovers.
The boys enter fourth grade, and suddenly wish they were back in the third grade. Meanwhile, the fourth grade teacher Ms. Choksondik seeks help in controlling the students from Mr. Garrison, who is now a hermit who won't come to terms with his homosexuality
A man from the future wants Cartman's new trapper keeper. Mr. Garrison's kindergarten class holds an election for class president with confusing results.
Cartman is sent to a weight loss camp. Kenny is paid to do disgusting stunts and becomes a TV star.
The boys, angry at their parents, send them to jail after saying they were "molestered", leaving the town to the children.
Kyle is upset over the fact that Mr. Hankey is too busy with his family to spread holiday cheer, so he and the other boys create a Christmas cartoon based on Parker and Stone's "The Spirit of Christmas" short.